Malas TB, Formica C, Leonhard WN, Rao P, Granchi Z, Roos M, Peters DJ, ‘t Hoen PA.
Am J Physiol Renal Physiol. 2017 Apr 1;312(4):F806-F817.
This article is published with contributions of GenomeScan.
“In this study, we present the first RNASeq analysis of a Pkd1-mutant mouse model in a combined meta-analysis with other published PKD expression profiles. We introduce the PKD Signature, a set of 1,515 genes that are commonly dysregulated in PKD studies.”
“We propose that compounds that can modulate the injury-repair response could be valuable drug candidates for PKD treatment.”