Next generation sequencing (NGS)
Unless you are only interested in a small number of specific genes, next generation sequencing offers you the most efficient option to sequence DNA. Even in targeted sequencing of specific genes, a high coverage of the region can help increase the quality of your data. Several advantages Next Generation Sequencing provides are listed here.
Over the past 15+ years, GenomeScan has acquired extensive experience in genomic sequencing applications. Whether you work with human, animal, bacterial or plant samples, we will discuss your experiment, define the output and tailor your sequencing project to your various research needs.
Our state-of-the-art instruments in combination with our scientific expertise result in the most efficient workflows for high-quality results. For example, in the past 4 years, we reduced the turnaround time of WES from 6 weeks to 6 days by developing new isolation and library preparation protocols as well as by optimizing the use of flow cells.
Rigorous bioinformatics analysis is an essential step in going from sequencing data to scientific results. GenomeScan has expertise in extracting genuine insights from this large set of data. Upon request, we perform in depth mining of your dataset using both proprietary and public pipelines. We build a comprehensive report that informs you on your next steps.
We use optimized workflows for samples that yield partially degraded DNA and apply quality controls to ensure data reliability and reproducibility. Our standard DNA sequencing services require as few as 20 cells (100 pg) as input material.