Graphene nanogaps for single molecule sequencing.
Controllable graphene nanogaps for single-molecule recognition.
Innovation, Project Management
Netherlands Organisation for Scientific Research (NWO) – Grant ID 16671
1 January 2019 to 1 January 2023
The project aims at fabrication of a new device concept for electrically recognizing single molecules and for sequencing biomolecules, including DNA and proteins, challenging current sequencing strategies through a novel architecture able to resolve single nucleobases. Reliably distinguishing individual building blocks in biomolecules (individual amino acids, individual nucleotides, individual molecule conformations) has, to date, been hampered by the size of the sensing volume. Graphene – a one-atom thin sheet of graphite – has the potential to remedy this problem, which is explored by this consortium. If successful, the project will pave the way towards a radically changed healthcare scenario, where DNA sequencing will be fast, cheap and portable and will enable to tailor medicine and treatments on genetic maps of the patients. GenomeScan participates in the user meetings providing an expertise in the Next Generation Sequencing.
T.b.a. (ongoing project)
This work is part of the NWO research programme with project number 16671, which is (partly) funded by the Dutch Research Council (NWO).