EU-Funded Project

imode ckd square iMODE CKD




Identification of the Molecular Determinants of established Chronic Kidney Disease.

In short:

Training programme studying molecular integration of chronic kidney disease determinants.


Human R&D, Training, Innovation

RD iMODE CKD Training iMODE CKD Innovation iMODE CKD

Project Details

Funding scheme:

FP7-PEOPLE-2013-ITN – Grant Agreement ID 608332

Time frame:

1 September 2013 to 31 August 2017



iMODE-CKD integrated multi-disciplinary expertise in proteomics, metabolomics, transcriptomics, bioinformatics, pathology, and clinical science from leading academic and industrial investigators, establishing a unique training platform on biomarker research and Systems Biology. Special emphasis was placed on the application of a wide range of –omics and bioinformatics techniques to clinical research. This educational scope was placed in the context of a significant research objective: to improve quality of life of patients with CKD and diminish the severe health and economic burden imposed by this disease, by providing better diagnostic and prognostic means. GenomeScan hosted one early stage researcher (ESR), organized a workshop on Commerce and Entrepreneurship. Furthermore, GenomeScan provided Next Generation Sequencing and Single Molecule Sequencing services and performed array-based expression profiling studies that were essential for establishing relation between gene expression and CKD progression.


Detecting PKD1 variants in polycystic kidney disease patients by single‐molecule long‐read sequencing. Borràs DM, et al. Human mutation. 2017 Jul;38(7):870-9. doi: 10.1002/humu.23223


EU iMODE CKD This project has received funding from the European Union’s Seventh Framework Programme (FP7/2007-2013) under grant agreement No 608332.