Bioinformatics

Data analysis and reporting

Giving meaning to your sequencing data.

Each sequencing project is unique and data analysis is crucial for the successful completion of your project. At GenomeScan, we keep listening to understand your constraints and your needs.

Our Bioinformaticians routinely perform custom analyses, including the development of new methods for mining and interpreting your biological data. When starting up a sequencing project, we always discuss the options for data analysis. You can choose to receive the quality controlled sequencing data in raw format (FASTQ) or opt for a detailed bioinformatics analysis.

Our bioinformatics team brings together expertise in next generation sequencing, validated data processing, statistics, bioinformatics, genetics, and genomics.

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Key benefits:

  • Add value (get the most biologically relevant information out of your data)
  • Flexible analysis (make use of an analysis strategy tailored to your needs) workflow image?
  • Results with confidence (we work under ISO/IEC 17025 or ISO 15189) link to quality page
  • Fast results (receive bioinformatics report in 48???h) link to example of report?

DNA Sequencing

Align raw NGS reads to analyze, identify and understand genomic variations and changes.

Whole genome (WGS), whole exome (WES), and targeted sequencing are ways to take a snapshot of the genetic landscape of your sample. Our team works with you to process your data, improve alignments and report genomic changes (SNPs, indels, SNV, CNV). We use industry-trandard pipelines to process your data from raw FASTQ files to an annotated variant list.

RNA Sequencing

Analyze continuous changing gene expression patterns.

Today RNA sequencing is not limited to standard gene expression or transcriptome analysis, GenomeScan developed protocols for small-, low input- and FFPE RNA sequencing. Various statistical analyses including sample correlation, principal component, differential gene expression analysis, gene set enrichment and pathway analyses are performed and presented in figures and tables to quickly identify key genes.

Epigenetics

Understand gene activity and regulation

Validated protocols and applications allow you to study different methylation loci in the most challenging samples: low quality or quantity of the available DNA is no longer hampering your project. Our bioinformaticianss analyse epigenetic NGS data, such as Bisulfite-Seq, ChIP-Seq, and RNA-Seq???, and extract biological insights to allow you to make educated and clear decisions.

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FAQ about Bioinformatics:

    1. Which software/pipelines do we use for analyses
    2. Do I get a report and how does a report looks like?
    3. Do I get intermediate files next to the result files?
    4. What versions of the software are you using?
    5. Can you perform the analysis according this paper or workflow?
Photo André rond 01 Bio IT

Andre Wijfjes

Manager Customer Support

+31 71 568 1036